Computational Biologist Postdoc Fellow
Be Part of Something Great!
The Life Sciences Division has an opportunity for a Computational Biologist Postdoctoral Fellow to participate in projects to characterize the time and dose dependencies of gene-expression response profiles after exposures of mammalian cells and tissues to low-dose ionizing radiation, to identify response pathways, and to identify co-regulatory determinants of susceptibility to genomic damage in irradiated cells.
As a Postdoc, you will:
- Participate in projects to characterize the time and dose dependencies of gene-expression response profiles after exposures of mammalian cells and tissues to low-dose ionizing radiation, to identify response pathways, and to identify co-regulatory determinants of susceptibility to genomic damage in irradiated cells.
- Conduct genomic-scale experiments of gene expression profiles in irradiated cells using gene-transcript microarrays with cells from human 2D or 3D cultures, and mouse tissues.
- Perform molecular validation of mRNA response patterns in irradiated cells.
- Apply and interpret biostatistical tools to identify time- and dose-dependent clusters and characterize their variability among tissue and cell types.
- Apply and interpret bioinformatics analyses of functions and pathways associated with radiation-responsive genes.
- Maintain an accurate and detailed laboratory notebook of all experiments performed
- Provide training and guidance to undergraduate and graduate students.
- Prepare results for publication in scientific journals and presentations at seminars and present research data at group meetings, seminars and conferences.
Key Success Factors
- Recent Ph.D. degree in computational biology, biophysics, or related field.
- At least two years of experience in research involving genomic structure, computational genomic analyses, and bioinformatics tools are required.
- Experience in analyzing data from genome-scaling expression technologies (gene-transcript and/or proteomic cellular analyses methods) is required.
- Training and understanding of biostatistics and genomic biology is required.
- Demonstrated ability to work with guidance of principal investigator and collaborators.
- Demonstrated ability to conduct experiments independently, maintain appropriate records and manage data.
- Excellent verbal and written communication skills.
- Proven ability to organize research results for publication.
Desired Traits
- Experience in various techniques used in molecular biology, immunostaining, RNA and DNA analysis, in mammalian cells.
- Experience in culture of human cells.
Notes
This is a two-year computational postoctoral appointment.
To apply: http://cjo.lbl.gov/LBNLCareers/details.asp?jid=23116&p=1
Berkeley Lab is an affirmative action/equal opportunity employer committed to the development of a diverse workforce.
Employer: Lawrence Berkeley National Laboratory
Location: Berkeley, CA, United States
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Tags: computational biologis, postdoc fellow
- July 22nd
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