MRC/Novartis funded PhD Studentship – Imperial College London

MRC/Novartis funded PhD Studentship
Imperial College London
Country: UK

Applications are invited from candidates with a degree in Biological Sciences or a related discipline, for a 3yr PhD studentship to investigate innate immune mediated responses in pulmonary fibrosis and in particular the role of mast cells. Studies will focus on the role of pattern recognition receptors in stimulating effector cell function.

The studentship will be funded for 3 years with a bursary of 15,743 per annum. Tuition fees at the Home/EU rate will also be paid. *Only Home and EU applicants who have been resident in UK for at least 3 years are eligible for this award. Overseas applicants are not eligible for this award. *

The student will work with the group of Dr Elizabeth Jarman, a Scientific Investigator in fibrotic lung disease, based at Novartis, Horsham and the academic supervisor will be Professor Jonathan Lamb in the Immunology and Infection Section, Division of Cell and Molecular Biology, Imperial College London.

The project will investigate the effect of deleting mast cells and pattern recognition receptors (including NALP3) in the development of lung fibrosis at a histological, protein and molecular level. In vivo reconstitution of mast cell deficient mice will elucidate the specific contribution of mast cell pattern recognition receptors to the development of lung fibrosis. The project brings together a variety of in vivo models, in vitro techniques and molecular biology.

Novartis Institutes for BioMedical Research (NIBR) is a global research organisation committed to discovering innovative medicines that treat disease and improve health. The Respiratory Research Centre at Horsham is the Novartis worldwide headquarters for respiratory research, employing over 300 scientists in a 42 million purpose-built centre.

The student will belong to Imperials Graduate Schools which provides a full programme of training in research and transferable skills.

How to Apply

We are looking for enthusiastic candidates who hold or expect to gain a first or upper-second class degree preferably in biological sciences or a related subject from a recognised academic institution. In addition, a Masters degree or equivalent is normally a prerequisite for research study at Imperial College London.

To apply please send a CV, a personal statement and the names and addresses of at least two academic referees by e-mail or by post to Prof Jonathan Lamb (, Room 6166, Sir Alexander Fleming Building, South Kensington Campus, Imperial College London, SW7 2AZ. Please note that candidates must fulfil College admissions criteria. Please assume that you have not been successful if you have not heard within a month of applying.

Application Deadline 31-Oct-10